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This cannabinoid receptor agonists framework a special collecting, nonetheless most are lipid-solvent and non-polar and comprise of twenty-two to 26 carbon molecules; they'd, in this manner, be relied upon to volatilize instantly when smoked.
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PB-22 and 5F-PB-22 have been the 1st artificial cannabinoids to include a quinoline substructure and an ester linkage. click here These compounds are assumed to have been synthesized Using the intention of constructing a synthetic cannabinoid prodrug, which could improve absorption and confound detection. Ester bonds are very easily biodegradable through spontaneous or endogenous, nonspecific esterase hydrolysis, which has been generally Utilized in medicinal chemistry to help make ester prodrugs.
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